Welcome to Kersville, a town with a spooky history and a collection of ghosts and spirits who are major mischief-makers. Most kids spend their days without ever seeing or dealing with a ghost, but some kids get stuck with a haunt. When that happens, they call Desmond Cole Ghost Patrol. Desmond is the hall monitor of ghosts and monsters. There's no job too spooky, icky, or risky for Desmond.

I'm not like that at all. My name's Andres Miedoso. I'm Desmond's best friend. We do everything together…including catch ghosts. Seems cool, right? There's only one problem: I'm afraid of everything.